Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy

Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy.

BACKGROUND The benefits of endoscopic testing for colorectal-cancer screening are uncertain. We evaluated the effect of screening with flexible sigmoidoscopy on colorectal-cancer incidence and mortality. METHODS From 1993 through 2001, we randomly assigned 154,900 men and women 55 to 74 years of age either to screening with flexible sigmoidoscopy, with a repeat screening at 3 or 5 years, or t...

Screening Flexible Sigmoidoscopy Reduces Colon Cancer Incidence and Mortality, But Compared with What?

Setting and participants. 154,900 men and women aged 55 to 74 years were enrolled between 1993 and 2001 at multiple U.S. medical centers and block randomized to either endoscopic CRC screening with flexible sigmoidoscopy (n = 77,445) or usual care (n = 77,455). Patients were excluded from the study if they had a history of prostate, lung, ovarian, or colorectal cancer or were undergoing current...

Flexible sigmoidoscopy for colorectal cancer screening: an evidence-based analysis.

Flexible sigmoidoscopy for colorectal cancer screening in Canada.

1Departments of Internal Medicine and Community Health Sciences, University of Manitoba; 2Department of Hematology and Oncology, CancerCare Manitoba; 3University of Manitoba IBD Clinical and Research Centre, Winnipeg, Manitoba; 4Division of Gastroenterology, Hepatology and Nutrition; University of Utah and Huntsman Cancer Institute, Salt Lake City, Utah; 5Division of Gastroenterology, Hepatolog...

Incomplete screening flexible sigmoidoscopy associated with female sex, age, and increased risk of colorectal cancer.

BACKGROUND Several previous studies have found that females and older individuals are at greater risk of having incomplete flexible sigmoidoscopy. However, no prior study has reported the subsequent risk of colorectal cancer (CRC) following incomplete sigmoidoscopy. METHODS Using data from 55 791 individuals screened as part of the Colon Cancer Prevention (CoCaP) programme of Kaiser Permanent...